I use the Betametazone only as a last resort, because I'm told it can be harmful with frequent use.
Generic betamethasone dipropionate 0.05% is also available in cream, ointment, and lotion forms, along with a gel form. FiftyAt baseline a questionnaire was filled for each patient including demographic data, degree of skin involvement, and systemic medication consumption.NAPSI of both hands’ fingers was calculated at baseline and six monthly follow-ups by a well-trained dermatologist in line with six monthly triamcinolone acetonide iontophoresis sessions and daily application of calcipotriol/betamethasone dipropionate ointment for six months. The minimum and the maximum number of nail involvements were four and ten, and the mean number of nail involvement in hands treated with TI and topical calcipotriol/betamethasone dipropionate were 4 ± 1.15 and 4.07 ± 1.At baseline, there was not difference between TI or calcipotriol/betamethasone dipropionate groups, regarding nail bed score (TI: 5.63 ± 3.59 versus calcipotriol/betamethasone dipropionate: 5.5 ± 3.5;Initial NAPSI reduction by TI after third and fourth follow-up was recorded for 7 (43.75%) and 13 (81.25%) patients, while it was achieved by topical calcipotriol/betamethasone dipropionate in 3 (18.75%) and 10 (62.5%) patients. Generic (regular) betamethasone dipropionate 0.05% is currently available in cream, ointment, and lotion forms. Bilateral complete response (NAPSI of zero) was observed in three patients.When comparing TI and calcipotriol/betamethasone dipropionate for the overall decrease (∆) in severity score, no difference between the therapeutic effect of TI and topical calcipotriol/betamethasone dipropionate was observed, regarding the nail bed score (TI (∆): −5.19 ± 3.25 versus calcipotriol/betamethasone dipropionate (∆): −4.5 ± 3.46,The mean ± SD of nail bed score, matrix score, and NAPSI at the baseline and six monthly follow-up visits for both treatments were shown at Table Considering the interventions separately, in the hands treated with TI a diminution pattern was observed for nail bed score (Patients’ satisfaction was evaluated by a visual analog scale (VAS) and no difference between the two therapies was observed (The puzzling treatment of nail psoriasis still remains unanswered, since topical treatments minimally influence nail involvements and systemic therapies are accompanied with several side effects such as hepatotoxicity, hypertension, renal dysfunction, immunosuppression, and severe infections, and hence they are not suitable for those with mild nail psoriasis without severe skin involvements [In a recently published review study on treatment strategies, all biologic agents including antitumor necrosis factor-a, anti-interleukin (IL) 17, and anti-IL-12/23 antibodies were introduced as the highly effective available therapies, followed by systemic therapies comprising methotrexate, cyclosporine, acitretin, and apremilast, as well as intralesional corticosteroids. Nothing, except it works for at least four days when I am desperate for relief and doctors won't give anything for pain. For the body, it’s 2 weeks on, 1 week off. Any author submitting a COVID-19 paper should notify us at Baseline characteristics; TI: triamcinolone acetonide iontophoresis; CB: calcipotriol/betamethasone dipropionate.Patient’s nail findings; TI: triamcinolone acetonide iontophoresis; CB: calcipotriol/betamethasone dipropionate.TI: triamcinolone acetonide iontophoresis, CB: calcipotriol/betamethasone dipropionate, and SD: standard deviation.Mean severity score reduction during the course of study.Mean nail bed, matrix, and NAPSI score reduction over the study; TI: triamcinolone acetonide iontophoresis; CB: calcipotriol/betamethasone dipropionate.
To avoid undertreatment, it’s important to specify on the prescription how much medication the pharmacy is to provide.
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