painful swelling of a leg, sudden pain in the chest, dyspnoea). Results of the WHI studies are presented:The risk of coronary artery disease is slightly increased in users of combined oestrogen-progestogen HRT over the age of 60 (see section 4.4).The use of oestrogen-only and oestrogen-progestogen therapy is associated with an up to 1.5-fold increased relative risk of ischaemic stroke.

• In women with no personal history of VTE but with a first degree relative with a history of thrombosis at young age, screening may be offered after careful counselling regarding its limitations (only a proportion of thrombophilic defects are identified by screening).

Unless there is a previous diagnosis of endometriosis, it is not recommended to add a progestogen in hysterectomised women.If the woman has an intact uterus and is still menstruating, a combination regimen with Progynova and a progestogen, commencing with the oestrogen phase, should begin on the first day of bleeding. Progynova 2 mg is used for "hormone replacement therapy" because it contains the principal oestrogen …

De meest voorkomende bijwerkingen van dit medicijn, zijn de volgende:De meeste bijwerkingen treden in de eerste weken van het gebruik van Progynova op en worden na verloop van tijd minder.

In Progynova 1 mg: geel ijzeroxide (E172). %���� Geneesmiddelengroep Progynova behoort tot de geneesmiddelen die oestrogenen bevatten. As the baseline absolute risk of CAD is strongly dependent on age, the number of extra cases of CAD due to oestrogen-progestogen use is very low in healthy women close to menopause, but will rise with more advanced age.Randomised controlled data found no increased risk of CAD in hysterectomised women using oestrogen-only therapy.Combined oestrogen-progestogen and oestrogen-only therapy are associated with an up to 1.5-fold increase in risk of ischaemic stroke.

1 0 obj Verpakkingsgrootte Progynova 1 mg en Progynova 2 mg zijn verkrijgbaar in verpakkingen van 1 strip à 21 tabletten. Let op! For more information see section 4.4 “Other conditions”.Progynova is not indicated during pregnancy. Progynova 2 mg Tablet is used to treat Hormone replacement therapy, Post menopausal osteoporosis, Contraception. Op uw verzoek regelen wij voor u een consult met een geregistreerde onafhankelijke EU-arts. A meta-analysis from 52 epidemiological studies reported an increased risk of ovarian cancer in women currently using HRT compared to women who have never used HRT (RR 1.43, 95% CI 1.31-1.56). It does not matter at what time of day the woman takes her tablet, but once she has selected a particular time she should keep to it every day. It does not matter at what time of day the woman takes her tablet, but once she has selected a particular time she should keep to it every day. • Epidemiological evidence from a large meta-analysis suggests a slightly increased risk in women taking oestrogen-only or combined oestrogen-progestogen HRT, which becomes apparent within 5 years of use and diminishes over time after stopping. The occurrence of such an event is more likely in the first year of HRT than later (see Section 4.8). • Women with pre-existing hypertriglyceridaemia should be followed closely during oestrogen replacement or hormone replacement therapy, since rare cases of large increases of plasma triglycerides leading to pancreatitis have been reported with oestrogen therapy in this condition.

Women should be advised what changes in their breasts should be reported to their doctor or nurse (see 'Breast cancer' below).

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