Once absorbed, the volume of distribution of isosorbide dinitrate is 2 to 4 L/kg, and this volume is cleared at the rate of 2 to 4 L/min, so ISDN’s half-life in serum is about an hour. This stimulates the synthesis of cyclic guanosine 3',5'-monophosphate (cGMP) which then activates a series of protein kinase-dependent phosphorylations in the smooth muscle cells, eventually resulting in the dephosphorylation of the myosin light chain of the smooth muscle fiber. While you are taking this medicine, be careful to limit the amount of alcohol you drink. Side effects include nausea, headache, and hot flashes.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

Your doctor may occasionally change your dose. Select one or more newsletters to continue.

Consult your Are you considering switching to Isosorbide Dinitrate?Are you planning to see a doctor about switching your medication?How long have you been taking Isosorbide Dinitrate?Are you planning to see a doctor about switching your medication?Selected from data included with permission and copyrighted by First Databank, Inc. This medicine may impair your thinking or reactions. Hydralazine and isosorbide dinitrate is a combination medicine used to treat heart failure. Used to help reduce swelling (edema) from excess buildup of fluid in the body.

Only the sublingual tablet should be used to treat an angina attack that has already begun. Completing the CAPTCHA proves you are a human and gives you temporary access to the web property.If you are on a personal connection, like at home, you can run an anti-virus scan on your device to make sure it is not infected with malware.If you are at an office or shared network, you can ask the network administrator to run a scan across the network looking for misconfigured or infected devices. Many people using this medication do not have serious side effects.Tell your doctor right away if any of these unlikely but serious side effects occur: This is not a complete list of possible side effects. If your doctor changes your brand, strength, or type of isosorbide dinitrate, your dosage needs may change. Enter the imprint code that appears on the pill e.g. Do not chew or swallow it.You may use the sublingual tablet within 15 minutes before an activity you think might cause chest pain. Once absorbed, the volume of distribution of isosorbide dinitrate is 2 to 4 L/kg, and this volume is cleared at the rate of 2 to 4 L/min, so isosorbide dinitrate's half-life in serum is about an hour. How to identify a pill using the Pill Identifier?

Your doctor may recommend treating Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. ISOSORBIDE DINITRATE (eye soe SOR bide dye NYE trate) is a type of vasodilator. Tell your doctor if you are pregnant or plan to become pregnant.It is not known whether isosorbide dinitrate passes into breast milk or if it could affect the nursing baby.

L484; Select the the pill color (optional) Select the shape (optional) You may also search by drug name or NDC code; Useful tip: Search for the imprint first, then refine by color and shape if you have too many results. If you notice other effects not listed above, contact your doctor or pharmacist.Call your doctor for medical advice about side effects.

Nitrates (drugs or medications) are prescription drugs used to treat and prevent angina (heart pain, chest pain). Isosorbide dinitrate is good for chest pain, but you have to be able to stick to your dosing schedule or it won't work as well. Skip the missed dose if your next dose is less than 2 hours away.If you are using the extended-release capsule or tablet and your next dose is less than 6 hours away, skip the missed dose and use the medicine at your next regularly scheduled time.Do not use extra medicine to make up a missed dose.Seek emergency medical attention if you think you have used too much of isosorbide dinitrate. Isosorbide dinitrate (ISDN) is 1,4:3,6-dianhydro-D-glucitol 2,5 dinitrate, an organic nitrate whose structural formula is: and whose molecular weight is 236.14.
Do not double the dose to catch up.Store at room temperature away from light and moisture. Hydralazine and isosorbide dinitrate may also be used for purposes not listed in this medication guide. Vasodilators Commonly prescribed include: Isosorbide dinitrate (Isordil) Isosorbide mononitrate (Imdur) Hydralazine (Apresoline) Nitroglycerin (Nitro Bid, Nitro Stat) Minoxidil; What the Medication Does We comply with the HONcode standard for trustworthy health information -

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